Muscle & Fitness logo Muscle & Fitness

  • Workouts

    Workouts

    • Workout Routines
    • Workout Tips
    • Fitness
    • Athlete/Celebrity Workouts
    • Exercise Videos
    Find Exercises Targeting…
    • Abs and Core Exercises
    • Arm Exercises
    • Back Exercises
    • Chest Exercises
    • Leg Exercises
    • Shoulder Exercises
  • Nutrition

    Nutrition

    • Healthy Eating
    • Lose Fat
    • Gain Mass
    • Supplements
    • Performance Nutrition
    Elderly japanese man eating with a young japanese boy practicing Hara Hachi Bu diet method
    Healthy Eating

    What is the hara hachi bu diet and how does it work?

    Girl holding a linear bar
    Healthy Eating

    Behind the Bar: Why Linear Bar’s Founder Decided the Protein Bar Industr...

    Female with a healthy gut health avoiding inflammation eating healthy non-processed foods recommended by a Gastroenterologist
    Healthy Eating

    Low Energy, Bloating, and Brain Fog? Your Gut Health Could Be the Reason...

    Korean side dish Kimchi holds nutritional benefits for gut health
    Healthy Eating

    What Science Says About the Immune-Boosting Power of Kimchi

  • Athletes & Celebrities

    Athletes & Celebrities

    • News
    • Interviews
    • Women
    • Pro Tips
    • Behind-the-Scenes
    • Videos
    IMG_5825
    Interviews

    Farmers Want a Healthy Wife

    WWE female wrester Chelsea Green shares her favorite quick and easy high protein bowl air frier recipe
    Pro Tips

    WWE’s Chelsea Green shares her high-protein bowl recipe

    Guinness World Record Holder Diana Batres lifting 166 lbs with her hair braids
    News

    Mexican Powerlifter Smashes 12-Year Strength Record With Her Hair

    Russell Dickerson ripping his shirt
    Interviews

    Russell Dickerson Reveals the Exact Workout Plan Keeping Him Shredded on...

  • Features

    Features

    • From our Partners
    • Active Lifestyle
    • M&F: Fit to Serve
    • Gear
    • News
    • Opinion
    Teenage boy flexing his biceps in the mirror
    News

    What Happens When Teen Boys Start Biohacking Puberty with Peptides

    Various athletes hieghts competing in their designated sport
    News

    Want to Dominate a Sport? Your Height May Decide Which One

    Muscular middle aged man improving his life longevity with strength exercises
    News

    New Longevity Study Finds Stronger People May Live Longer

    Athletic young man listening to a workout playlist while performing a cardio workout on an exercise bike
    News

    Your Workout Playlist May Be Boosting Your Endurance

  • Anti-Aging

    Anti-Aging

    • Functional Medicine
    • Hormone Optimization
    • Recovery
    • Wellness
    Wellness retreat attendees performing yoga at SHA wellness retreat
    Wellness

    Can Your Biomarkers Build A Vacation Itinerary?

    Elderly man placing weights on a barbell
    Wellness

    Strength Training Is the New Anti-Aging Drug

    Supplement stack
    Functional Medicine

    The 5-Supplement Stack That Slows Aging and Boosts Muscle Growth

    Muscular and fit athlete next to a peptide compound
    Functional Medicine

    Are Peptides a Performance Breakthrough or Manufactured Controversy?

  • Flex

    Flex

    • Olympia Coverage
    • Athletes
    • Nutrition
    • Training
    • Videos
    TMP
    News

    Is Samson Dauda the new Ronnie Coleman?

    Hadi Choopan partners with Milos Sarcev for 2026 Mr. Olympia Comeback
    News

    Hadi Choopan Teams With Milos Sarcev for Mr. Olympia Comeback

    Bodybuilder John Jewett workout for quads and hamstrings muscle development
    Training

    John Jewett Reveals the Workout That Built His 'Horse Legs'

    2026 Pittsburgh Pro winner Michal Krizanek
    News

    Michal Krizanek Defeats Tonio Burton at Pittsburgh Pro

  • Hers

    Hers

    • Workouts
    • Nutrition
    • Supplements
    • Athletes & Celebrities
    • Features
    Female bodybuilder Erin Stern performing her lower body workout and top 3 inner thigh exercises for a tone and sculpted legs
    Hers Workouts

    These 3 Exercises Will Transform Your Inner Thighs—Fast

    social media fitness influencer and inspirational personal trainer, Stephanie Sanzo performs her birthday leg day workout
    Hers Workouts

    Stephanie Sanzo Proves Age Is Just a Number Each Leg Day

    Fitness Coach Anna McManamey-Cashion shares her tips for a post-binge reset for fitness and a healthy gut
    Muscle & Fitness Hers

    3 Proven Post-Binge Tips to Get Back on Track Fast

    Tiffany Stratton
    Muscle & Fitness Hers

    Tiffany Stratton Is Prepping for Her Return to Another Stage

  • Olympia

    Olympia

    • Olympia Coverage
    • Buy Tickets
    Caesar Bacarella performing a dumbbell workout with biceps curls
    Pro Tips

    Caesar Bacarella Is Building a Fitness Empire at Full Speed

    Olympia-2019-Whiteny-Jones-Press-Conference
    Interviews

    Whitney Jones Can Break, But Can Never Be Broken

    IFBB Wellness Pro Yarishna Ayala
    Interviews

    Yarishna Ayala Shares Advice for Future Wellness Division Competitors

    2021 Mr. Olympia Top 3 winners Brandon Curry, Big Ramy, Hadi Choopin
    News

    BIG RAMY WINS THE 2021 OLYMPIA!

Subscribe to YouTube Subscribe to the Newsletter Terms of Use Privacy Policy Cookie Policy Accessibility Statement Do Not Sell
  • Workouts
    • Workout Routines
    • Workout Tips
    • Fitness
    • Athlete/Celebrity Workouts
    • Exercise Videos
  • Nutrition
    • Healthy Eating
    • Lose Fat
    • Gain Mass
    • Supplements
    • Performance Nutrition
  • Athletes & Celebrities
    • News
    • Interviews
    • Women
    • Pro Tips
    • Behind-the-Scenes
    • Videos
  • Features
    • From our Partners
    • Active Lifestyle
    • M&F: Fit to Serve
    • Gear
    • News
    • Opinion
  • Anti-Aging
    • Functional Medicine
    • Hormone Optimization
    • Recovery
    • Wellness
  • Flex
    • Olympia Coverage
    • Athletes
    • Nutrition
    • Training
    • Videos
  • Hers
    • Workouts
    • Nutrition
    • Supplements
    • Athletes & Celebrities
    • Features
  • Olympia
    • Olympia Coverage
    • Buy Tickets
  • Resources & Highlights
    • Topics
    • Videos
    • Podcasts
    • Contact
    • Terms of Use
    • Privacy Policy
    • Cookie Policy
    • Accessibility Statement
    • Do Not Sell

Stay Connected

Newsletter Signup

Stay up to date

Sign up below to receive our newest workout routines, recipes, news stories, and offers from our partners

Facebook Twitter Youtube Pinterest
Open menu button
Open search bar button
×

Search M&F

Featured Articles
Lean Muscle
Healthy Eating

28-Days-to-Lean Meal Plan

With the right plan and the right discipline, you can get seriously shredded in just 28 days.

Read article
Glamorous Hollywood actress in a black evening gown posing at a red carpet event, representing one of the hottest female celebrities in Hollywood
Women

The 25 Hottest Female Celebrities

Talented stars, killer physiques.

Read article
Bench press record holder Bill Gillespie breaking the world record at age 62
Pro Tips

The 'Dos' and 'Don’ts' of Bill Gillespie’s Record-Breaking Bench Press

At age 62, "Big Bill" shares his wisdom to dominate one of the ultimate strength marks.

Read article
The 50 Best Female Fitness Influencers on Instagram
Girls

The 50 Best Fitness Influencers on Instagram

Follow these fit women we're crushing on for inspiration, workout ideas, and motivation.

Read article
Lose Fat

Pump and Burn: Supps for Bulking and Cutting

Forget arduous "leaning-out"” cycles. Stay both big and cut year-round with this potent quartet of muscle-building, fat-fighting supplements.

by M&F Editors
  • Click to share on Facebook (Opens in new window)
  • Click to share on Twitter (Opens in new window)
  • Click to share on Pinterest (Opens in new window)
  • Click to share on Facebook (Opens in new window)
  • Click to share on Twitter (Opens in new window)
  • Click to share on Pinterest (Opens in new window)
Pump and Burn: Supps for Bulking and Cutting
View Gallery

Pump and Burn: Supps for Bulking and Cutting

Close gallery popup button
1 OF 6

1 of 6

Pump and Burn: Supps for Bulking and Cutting

For years, bodybuilding was a cyclical act with aspiring Mr. Olympias and gym rats alike going back and forth between mass phases and leaning-out phases because we all thought we couldn’t grow lean muscle and drop body fat simultaneously.The result was off-season gorging that left many bodybuilders looking more like circa-1995 Oprah than circa-1975 Arnold Schwarzenegger heading into a contest. Unfortunately, this approach led to drastic dieting before hitting the stage, leading many competitors to miss their peak by coming in too heavy and flabby or too light and depleted. Today’s smarter bodybuilders know they can stay fairly lean year-round and still add muscle. With a lot of science and little trial and error, the fitness world has found more efficient ways to look your Sandow best.You can choose from among several approaches to stay lean and large in any season. A diet lower in carbs and high in protein is one reliable method for staying trim, but stacking the right supplements can also help fill out your muscle bellies and bring out your six-pack. Combining nitric oxide (NO)-boosters with fat-burners provides all the muscle-building effects of NO supplements with fat-melting effects. And if the muscle-pumping effects of NO weren’t enough, research now shows that it plays a critical role in fat-burning. So it’s time to contemporize. Getting big and lean can now be a 365-days-a-year endeavor.

2 of 6

l-arginine

L-Arginine

The amino acid arginine occurs naturally in the body and is also found in foods like poultry, red meat, dairy and legumes. NO is a gas produced in the body from the amino acid arginine, which is why almost every NO-booster on the market contains some form of arginine. L-arginine happens to be the simplest and cheapest form of the amino acid, but that doesn’t mean it’s less effective. NO is responsible for countless processes in the body, including the dilation of blood vessels to allow more blood flow to tissues such as muscle. This allows more oxygen, nutrients, anabolic hormones and supplements that have been taken to reach the muscle fibers, leading to more growth. Taking fat-burners with arginine can help deliver more of the ingredients to your muscles and other tissues for a greater effect. In addition, NO appears to have its own effects on fat-burning. French scientists report that NO enhances lipolysis (the breakdown and release of fat) in the fat cells. This means more body fat is available to burn.DOSE: 1-5 grams of L-arginine 2-3 times daily, with one dose 30-60 minutes before workouts.Get L-Arginine >>

3 of 6

Metafolin

Metafolin

This is a patented form of the B vitamin folate technically known as L-methylfolate. Folate is a vitamin necessary for the production and maintenance of new cells. Since bodybuilding involves the building of new muscle cells, this is crucial for muscle growth. Folate is also needed to make DNA and RNA, the building blocks of cells. Since muscles also grow through this mechanism, folate is essential for lifters wanting to add some beef to their frames. But folate is no one-dimensional nutrient—it also plays a role in the production of NO from arginine by regulating the co-factors that directly influence the amount of arginine that can be converted to NO. The more arginine converted, the greater the resulting NO production. When regular dietary folate, or folic acid found in foods like leafy greens, citrus fruits and whole grains, is absorbed by the body, it has to get converted to the active form, L-methylfolate. Taking folate that’s already in the active form, such as Metafolin, means no conversion is required, which allows more of it to be used by the body.DOSE: 400-800 mcg of Metafolin with arginine at the same times throughout the day.Get Metafolin >>

4 of 6

citrus aurantium

Citrus Aurantium

Commonly referred to as bitter orange, this plant contains the active ingredient synephrine, which is chemically similar to ephedrine but doesn’t have any of the negative side effects, such as elevated heart rate and blood pressure. Synephrine works by stimulating receptors on fat cells that increase lipolysis, decrease appetite and raise metabolic rate—all massive contributors to overall body fat reduction.DOSE: 200-600 mg citrus aurantium (standardized for synephrine, for a total dose of 5-20 mg of synephrine) 2-3 times daily.

5 of 6

Hops Extract

Hops Extract

This extract is from the same hops flowers (humulus lupulus) used to brew beer. Hops has anti-inflammatory properties, making it good for joint health. It’s often used for its calming effects as a sleep aid at higher doses, but that doesn’t mean you should down a twelver to soothe your ailing knees. Hops contains the active ingredients isohumulones, which contribute to the bitter taste of beer and help burn fat. Research shows that isohumulones may help decrease body fat in several ways—by reducing the amount of fat the intestines absorb, activating genes that increase fat oxidation (fat-burning) and lessening the activity of genes involved in the storage of body fat, which means less fat gets stored.DOSE: 100-400 mg of hops extract 2-3 times daily.

6 of 6

6 Reasons Supersets are Super Effective for Building Muscle

Large and Lean Stack

Take these four supplements together three times per day, with one dose about 30-60 minutes before workouts. Take the other two doses in the morning and early afternoon. You can buy each supplement individually or purchase a product that contains all four.SupplementRecommended DoseL-Arginine1-5 gMetafolin400-800 mcgCitrus Aurantium200-600 mg (5-20 mg synephrine)Hops Extract100-400 mg

Back to intro

For years, bodybuilding was a cyclical act with aspiring Mr. Olympias and gym rats alike going back and forth between mass phases and leaning-out phases because we all thought we couldn’t grow lean muscle and drop body fat simultaneously.

The result was off-season gorging that left many bodybuilders looking more like circa-1995 Oprah than circa-1975 Arnold Schwarzenegger heading into a contest. Unfortunately, this approach led to drastic dieting before hitting the stage, leading many competitors to miss their peak by coming in too heavy and flabby or too light and depleted. Today’s smarter bodybuilders know they can stay fairly lean year-round and still add muscle. With a lot of science and little trial and error, the fitness world has found more efficient ways to look your Sandow best.

You can choose from among several approaches to stay lean and large in any season. A diet lower in carbs and high in protein is one reliable method for staying trim, but stacking the right supplements can also help fill out your muscle bellies and bring out your six-pack. Combining nitric oxide (NO)-boosters with fat-burners provides all the muscle-building effects of NO supplements with fat-melting effects. And if the muscle-pumping effects of NO weren’t enough, research now shows that it plays a critical role in fat-burning. So it’s time to contemporize. Getting big and lean can now be a 365-days-a-year endeavor.

L-Arginine

The amino acid arginine occurs naturally in the body and is also found in foods like poultry, red meat, dairy and legumes. NO is a gas produced in the body from the amino acid arginine, which is why almost every NO-booster on the market contains some form of arginine. L-arginine happens to be the simplest and cheapest form of the amino acid, but that doesn’t mean it’s less effective. NO is responsible for countless processes in the body, including the dilation of blood vessels to allow more blood flow to tissues such as muscle. This allows more oxygen, nutrients, anabolic hormones and supplements that have been taken to reach the muscle fibers, leading to more growth. Taking fat-burners with arginine can help deliver more of the ingredients to your muscles and other tissues for a greater effect. In addition, NO appears to have its own effects on fat-burning. French scientists report that NO enhances lipolysis (the breakdown and release of fat) in the fat cells. This means more body fat is available to burn.

DOSE: 1-5 grams of L-arginine 2-3 times daily, with one dose 30-60 minutes before workouts.

Get L-Arginine >>

Metafolin

This is a patented form of the B vitamin folate technically known as L-methylfolate. Folate is a vitamin necessary for the production and maintenance of new cells. Since bodybuilding involves the building of new muscle cells, this is crucial for muscle growth. Folate is also needed to make DNA and RNA, the building blocks of cells. Since muscles also grow through this mechanism, folate is essential for lifters wanting to add some beef to their frames. But folate is no one-dimensional nutrient—it also plays a role in the production of NO from arginine by regulating the co-factors that directly influence the amount of arginine that can be converted to NO. The more arginine converted, the greater the resulting NO production. When regular dietary folate, or folic acid found in foods like leafy greens, citrus fruits and whole grains, is absorbed by the body, it has to get converted to the active form, L-methylfolate. Taking folate that’s already in the active form, such as Metafolin, means no conversion is required, which allows more of it to be used by the body.

DOSE: 400-800 mcg of Metafolin with arginine at the same times throughout the day.

Get Metafolin >>

Citrus Aurantium

Commonly referred to as bitter orange, this plant contains the active ingredient synephrine, which is chemically similar to ephedrine but doesn’t have any of the negative side effects, such as elevated heart rate and blood pressure. Synephrine works by stimulating receptors on fat cells that increase lipolysis, decrease appetite and raise metabolic rate—all massive contributors to overall body fat reduction.

DOSE: 200-600 mg citrus aurantium (standardized for synephrine, for a total dose of 5-20 mg of synephrine) 2-3 times daily.

Hops Extract

This extract is from the same hops flowers (humulus lupulus) used to brew beer. Hops has anti-inflammatory properties, making it good for joint health. It’s often used for its calming effects as a sleep aid at higher doses, but that doesn’t mean you should down a twelver to soothe your ailing knees. Hops contains the active ingredients isohumulones, which contribute to the bitter taste of beer and help burn fat. Research shows that isohumulones may help decrease body fat in several ways—by reducing the amount of fat the intestines absorb, activating genes that increase fat oxidation (fat-burning) and lessening the activity of genes involved in the storage of body fat, which means less fat gets stored.

DOSE: 100-400 mg of hops extract 2-3 times daily.

Large and Lean Stack

Take these four supplements together three times per day, with one dose about 30-60 minutes before workouts. Take the other two doses in the morning and early afternoon. You can buy each supplement individually or purchase a product that contains all four.

Supplement

Recommended Dose

L-Arginine

1-5 g

Metafolin

400-800 mcg

Citrus Aurantium

200-600 mg (5-20 mg synephrine)

Hops Extract

100-400 mg

Author picture
Written by M&F Editors
Also by M&F Editors
Olympia Expo
News

Olympia Announces B2B Growth Opportunity for Sponsors and Exhibitors

Person holding a health and wellness icon while shopping online
Gear

Editor’s Choice: The Top 10 Health & Wellness Brands to Know

Newsletter Signup

Stay up to date

Sign up below to receive our newest workout routines, recipes, news stories, and offers from our partners

Muscle & Fitness logo

Follow us

Facebook Twitter Youtube Pinterest

More news

Bottle of Nutrition Probiotic D.R. 30 by Evogen Nutrition
Lose Fat

Boost Digestion and Immunity the Easy Way!

Boost digestion and immunity the easy way!

Read article
Instant Knockout Review
Lose Fat

Instant Knockout Review: I Tried It! Here’s My Results

I tried a fat burner called Instant Knockout and here’s what happened..

Read article
Muscular bodybuilder doing a kettlebell workout while using fat burning supplements for 2021
Lose Fat

The Top 10 Fat Burners For 2021

Today, more than ever having a shredded physique is a status symbol revered by many and sought by many many more.

Read article
All Lose Fat
  1. Home
  2. /
  3. Supplements
  4. /
  5. Lose Fat
  6. /
  7. Pump and Burn: Supps for Bulking and Cutting
Muscle & Fitness logo
  • Workouts
  • Nutrition
  • Athletes & Celebrities
  • Features
  • Recipes
  • Topics
  • Videos
  • Exercise Videos
  • Podcasts
  • RSS Feed
  • Buy Olympia Tickets
  • Archives
  • Sitemap
Facebook Twitter Youtube Pinterest

Newsletter Signup

Stay up to date

Sign up below to receive our newest workout routines, recipes, news stories, and offers from our partners

JW Media, LLC

Copyright 2026 JW Media, LLC, parent company of Muscle & Fitness. All rights reserved.

Contact Us Terms of Use Privacy Policy Cookie Policy Do Not Sell Accessibility Statement